Treatment of elevated histamine and uric acid levels

Details Treatment of elevated histamine and uric acid levels Treatment of elevated histamine and uric acid levels

1976-04-05

1977-05-17

Rosen, Sam

Drug, bio-affecting and body treating compositions

Antigen, epitope, or other immunospecific immunoeffector

Virus or component thereof

424308, 424311, A61K 3160, A61K 31235, A61K 3122

Patent

active

040242536

ABSTRACT:
Compounds having the general formula ##STR1## (the meanings of R.sup.1, R.sup.2, R.sup.3, R.sup.4 and R.sup.5 are indicated hereinafter) and the pharmaceutically acceptable salts and esters thereof exhibit strong activities in inhibiting histidine decarboxylase and xanthine oxidase and are useful for treating elevated histamine and uric acid levels. One example is the compound of the formula ##STR2##

REFERENCES:
chem. Abst. 8th Collective Index, vol. 66-75 (1967-1971) pp. 14983s and 32531s.

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