Substituted phenylguanidines and processes for their preparation

Details Substituted phenylguanidines and processes for their preparation Substituted phenylguanidines and processes for their preparation

1976-05-26

1977-05-17

Mars, Howard T.

Chemistry of carbon compounds

Miscellaneous organic carbon compounds

C-metal

C07C14940

Patent

active

040241769

ABSTRACT:
N-[2-(Substituted amido)phenyl]-N',N"-bis-carbonylguanidines bearing an optionally substituted phenoxy, phenylthio, phenylsulfinyl or phenylsulfonyl group in the 4- or 5-position of the 2-(substituted amido)-phenyl group are anthelmintic agents. The compounds, of which N-(2-acetamido-4-phenylthiophenyl)-N',N"-bis-carbomethoxyguanidine is a typical example, are prepared through the reaction of isothiourea-S-alkyl ether and an appropriately substituted 2-aminoanilide.

REFERENCES:
patent: 3828094 (1974-08-01), Widdig et al.

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