Process for the preparation of cephem derivatives and intermedia

Organic compounds -- part of the class 532-570 series – Organic compounds – Heterocyclic carbon compounds containing a hetero ring...

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540225, C07D50124

Patent

active

051284650

ABSTRACT:
A cephem derivative represented by the following formula: ##STR1## wherein R.sub.1 means a fluorine-substituted lower alkyl and A.sub.1 denotes a cyclic or acyclic ammonio group, or a non-toxic salt thereof, is prepared by reacting a compound represented by the following formula: ##STR2## wherein A.sub.1 has the same meaning as defined above, with another compound represented by the following formula: ##STR3## wherein R.sub.1 has the same meaning as defined above, and if necessary, removing the protecting groups.

REFERENCES:
patent: 4486586 (1984-12-01), Narita et al.
patent: 4632918 (1986-12-01), Angerbauer et al.
patent: 4751295 (1988-06-01), Oka et al.
patent: 4921850 (1990-05-01), Kamiya et al.

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