Bis-aryl amide and urea antagonists of platelet activating facto

Details Bis-aryl amide and urea antagonists of platelet activating facto Bis-aryl amide and urea antagonists of platelet activating facto

1990-05-04

1992-07-07

Dentz, Bernard

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

514369, 548187, 548200, 548204, A61K 31425, C07D27730

Patent

active

051283514

ABSTRACT:
Bis-aryl amide and urea compounds of the general formula: ##STR1## wherein X is a divalent amide or urea substituent and Y is a nitrogen containing heterocycle, which compounds are inhibitors of platelet activating factor. Pharmaceutical compositions containing the compounds and methods of treating platelet activating factor associated conditions are also included.

REFERENCES:
patent: 4692450 (1987-09-01), Cassal et al.

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