Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Phosphorus containing other than solely as part of an...
Patent
1989-10-25
1992-02-18
Shah, Mukund J.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Phosphorus containing other than solely as part of an...
514 63, 514471, 514473, 549214, 549222, 549313, 549318, 562840, A61K 31665, A61K 31365, C07F 9655, C07D30760
Patent
active
050894854
ABSTRACT:
New furanone compounds have anti-inflammatory, immunosuppressive and anti-proliferative activity and are useful in treating psoriasis and modifying calcium homeostasis. A compound of the invention is 4-(1-thioacetoxytridecyl-5-hydroxy-2(5H)-furanone.
REFERENCES:
patent: 2359096 (1944-09-01), Elderfield
patent: 2359208 (1944-09-01), Elderfield
patent: 4447445 (1984-05-01), Jacobs et al.
patent: 4786651 (1988-11-01), Wheeler
patent: 4789749 (1988-12-01), Jacobs et al.
patent: 4855320 (1989-08-01), Chatterjee et al.
patent: 4957917 (1990-09-01), Lee
patent: 5013850 (1991-05-01), Lee
patent: 5037811 (1991-08-01), Lee
patent: 5043457 (1991-08-01), Lee
patent: 5045564 (1991-09-01), Lee
Bennett et al., Molecular Pharmacology 32 p. 587 (1987).
Bonjouklian, et al., Chemical Abstracts, vol. 106, 156260c, p. 670 (1987).
Reynolds, et al., J. Am. Chem. Soc., 110, pp. 5172-5177 (1988).
Tocanne et al., Chemical Abstracts 69 76581k, p. 7146 (1968).
Deems, et al. Biochimica et Biophysica Acta, 917 pp. 258-268 (1987).
E. D. de Silva et al., "Tetrahedron Letters", 21:1611-1614 (1980).
Scheuer et al., Journal of the American Chemical Society 100:1, p. 307 (Jan. 4, 1978).
Graziano, et al., Chemical Abstracts 107, (1987), 236559t.
Roll et al., Org. Chem. 1988, 53 3276-8.
Negishi et al., J. Org. Chem. 45, pp. 5223-5225, (1980).
Nakagawa et al., "Aldose reductase inhibitor from Palaun sponges", Chem. Abstract 106: 96126b (1987).
Allergan Inc.
Baran Robert J.
Bernhardt E.
Shah Mukund J.
Szekeres Gabor L.
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