Polypeptides and process for the production thereof

Details Polypeptides and process for the production thereof Polypeptides and process for the production thereof

1989-03-07

1992-02-18

Martinell, James

Chemistry: molecular biology and microbiology

Micro-organism, tissue cell culture or enzyme using process...

Recombinant dna technique included in method of making a...

435 91, 4351723, 4352401, 4352523, 43525233, 4353201, 536 27, 935 11, C12P 2102, C12N 1500, C12N 1520, C12N 1521, C12N 1570

Patent

active

050894005

ABSTRACT:
Recombinant DNA molecules and hosts transformed with them are described which produce polypeptides displaying a human lymphoblastoid interferon activity. There are also provided processes for the preparation of said recombinant DNA molecules, said hosts, and said lymphoblastoid interferon-like polypeptides. The polypeptides of the invention are useful as immunomodulators, especially as antiviral, antitumor and anticancer agents.

REFERENCES:
Maniatis et al; Cell 15: 687 (1978).
M. Streuli et al., Proc. Natl. Acad. Sci. U.S.A. 78, 2848-2852 (1981).
M. D. Edge et al., Nature 292, 756-761 (1981).

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