Surgery – Truss – Perineal
Patent
1984-05-25
1987-06-09
Nucker, Christine M.
Surgery
Truss
Perineal
128 13, 128654, 128659, 264 41, 264 432, 424 11, 424 9, 4284022, A61K 4900, A61B 505, A61B 608, A61N 500
Patent
active
046712569
ABSTRACT:
A system and method for detecting, monitoring and treating a malady such as a disease in a living being. In one form, a dose of a drug formed of a multitude of drug units containing antibodies and a nuclide or nuclides is administered to a living being having one or more disease sites, such as malignant tumors or other forms of malignancy wherein the antibodies target the units to antigens at the disease site. Such targeting concentration of drug units is detected by scanning radiation generated either by radioactive nuclides tagged to the drug units or by activating normally inactive nuclide material in the drug units with radiation such as neutrons generated externally of the living being and directed through the body. The results obtained are employed to control the positioning and operation of one or more neutron beam generators for controllably directing a beam of neutrons through the body to the disease site to activate nuclide material targeted thereat and cause same to generate local cell killing radiation such as high velocity particles of reaction. Detection and monitoring of radiation generated when miniature nuclear explosions occur locally is automatically effected to determine the effect and results of such treatment. If required, one or more repeated administrations of the drug and its activation at the site or sites of the disease are effected, preferably under computer control. The system and method also provide for the detection and monitoring of malignancies and the like by means of X-rays or other form of radiation passed through the body of the patient being treated.
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