Heterocyclic substituted imidazo [1,2-a] pyridines

Details Heterocyclic substituted imidazo [1,2-a] pyridines Heterocyclic substituted imidazo [1,2-a] pyridines

1978-05-30

1979-03-27

Rotman, Alan L.

Drug, bio-affecting and body treating compositions

Antigen, epitope, or other immunospecific immunoeffector

Bacterium or component thereof or substance produced by said...

546121, C07D48704, A01N 922, A61K 3144

Patent

active

041466420

ABSTRACT:
Certain novel substituted imidazo [1,2-a] pyridines with a substituted amino group at the 2- or 3- position and a heterocyclic moiety on the pyrido portion of the molecule are active anthelmintic agents. The heterocyclic moiety is connected to the imidazo [1,2-a] pyridine molecule through an oxygen, sulfur, sulfinyl or sulfone. The novel compounds are prepared from the appropriately substituted 2-amino pyridine precursor. Compositions which utilize said novel imidazo [1,2-a] pyridines as the active ingredient thereof for the treatment of helminthiasis are also disclosed.

REFERENCES:
patent: 3701780 (1972-10-01), Fisher
patent: 4028370 (1977-06-01), Irikura
Fisher et al., Journal Medicinal Chemistry, vol. 15, (No. 9), pp. 982-985 (1972).

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