1-(P-Alkanoylphenyl) alkanols and derivatives

Drug – bio-affecting and body treating compositions – Antigen – epitope – or other immunospecific immunoeffector – Recombinant or stably-transformed bacterium encoding one or...

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260592, 260591, 2603405R, 2603407, C07C 4982, A01N 924

Patent

active

040512614

ABSTRACT:
1-(p-alkanoylphenyl) alkanols, e.g., 1-(p-acetophenyl)-2,2-dimethylpropanol, are prepared from p-alkanoylphenyl Grignard reagents and alkyl and aryl aldehydes or acyl or aroyl halides and are useful as hypolipidemic and anti-diabetic agents.

REFERENCES:
patent: 2438125 (1948-03-01), Lorand et al.
patent: 2495904 (1950-01-01), Pines et al.
patent: 2634294 (1953-04-01), Butler
patent: 2780649 (1957-02-01), Williams
patent: 3873539 (1975-03-01), Houlihan et al.
McOmie, Protective Groups in Organic Chemistry, pp. 325-327, (1973).

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