Certain 4,6-dihydropyrrolotriazoline-quinoline derivatives

Details Certain 4,6-dihydropyrrolotriazoline-quinoline derivatives Certain 4,6-dihydropyrrolotriazoline-quinoline derivatives

1975-05-19

1976-08-31

Rizzo, Nicholas S.

Chemistry of carbon compounds

Miscellaneous organic carbon compounds

C-metal

424258, C07D47116

Patent

active

039780660

ABSTRACT:
1,3-Dihydropyrrolo[4,3,2-de]isoquinoline derivatives characterized by an amino or hydrazino substituent at position 5 are disclosed. Also included are the related 4,6-dihydropyrrolo[4,3,2-de]-s-triazolo[3,4-a]isoquinoline and its 8-methyl derivative. The compounds are antidepressant and antihypertensive agents. Methods for their preparation and use are disclosed.

REFERENCES:
patent: 3272804 (1966-09-01), Archer et al.
patent: 3833591 (1974-09-01), McManus
patent: 3900477 (1975-08-01), Philipp et al.
Horning et al; Can. J. Chem. 49, pp. 2797-2802 (1971).

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