Benzothiazolesulfonamide derivatives for the topical treatment o

Details Benzothiazolesulfonamide derivatives for the topical treatment o Benzothiazolesulfonamide derivatives for the topical treatment o

1982-05-21

1983-11-22

Gerstl, Robert

Drug, bio-affecting and body treating compositions

Antigen, epitope, or other immunospecific immunoeffector

Parasitic organism or component thereof or substance...

548166, 546270, 424263, C07D27780, A61K 31425

Patent

active

044168900

ABSTRACT:
Novel carboxylic acid esters of 6-hydroxy-2-benzothiazolesulfonamide are shown to be useful for the topical treatment of elevated intraocular pressure. Ophthalmic compositions including drops and inserts are also disclosed, as well as methods for preparing the novel compounds.

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J5 7004-978 Chem. Abstract of Japan 79883.
Akerfeldt, S., J. of Med. Chem., 1970, vol. 13, No. 5, 1012-1013.
Org. Syn. with Noble Metal Catalysts, pp. 95-97 (1973).
Fiesen, Reagents for Organic Synthesis vol. 2, pp. 426-427 (1970).
Sandler, Org. Functional Group Preparations, pp. 253-254 (1968).

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