Nucleosides and nucleotide analogues, pharmaceutical composition

Details Nucleosides and nucleotide analogues, pharmaceutical composition Nucleosides and nucleotide analogues, pharmaceutical composition

1991-11-20

1993-06-01

Brown, Johnnie R.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Carbohydrate doai

514 50, 536 23, 536 2852, 536 2853, A61K 3170

Patent

active

052159701

ABSTRACT:
A compound of the formula ##STR1## wherein the radicals A, X, R.sup.1, R.sup.2 and R.sup.3 are defined as follows: ##STR2## R.sup.2 : H; or R.sup.2 constitutes together with R.sup.3 with a carbon - carbon bond

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Journal of Medicinal Chemistry, vol. 17, No. 3, 1974 T. Kulikowski et al. "5-Alkylpyrimidine Nucleosides. Preparation and Properties of 5-Ethyl-2'-deoxycytidine and Related Nucleosides", see pp. 269-273.
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J. Carbohydrates Nucleosides Nucleotides, vol. 5, No. 3, 1978, E. Declerq et al., "Nucleosides analogs with selective antiviral activity", see pp. 187-224.
Suito et al.: Nucleosides & Nucleotides, 1(3), 263-273 (1982): Chemical Conversion of Uridine to 3'-Branched Sugar Nucleosides (Nucleosides and Nucleotides, 42.sup.I.)

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