Steroid ethers

Details Steroid ethers Steroid ethers

1976-07-29

1977-09-27

Roberts, Elbert L.

Chemistry of carbon compounds

Miscellaneous organic carbon compounds

C-metal

C07J 7100

Patent

active

040511286

ABSTRACT:
Novel steroid ethers are disclosed, which are represented by the formula: ##STR1## wherein Z is selected from the group consisting of >C=O >CHOH, and ##STR2## X is selected from the group consisting of --H and --OH, and R is selected from the group consisting of ##STR3## wherein R.sub.1 is a straight or branched chain hydrocarbon of from 1 to about 16 carbon atoms; A is selected from the group consisting of --CH.sub.2 --, >C=O, and >CHOR.sub.3 ; Y may be a single bond or a double bond; R.sub.2 and --R.sub.1 O-- represent substituents on the aromatic ring of the group of the second formula, in either the 2 or 4 positions, and R.sub.2 is selected from the group consisting of H and OR.sub.3 ; R.sub.3 is selected from the group consisting of lower alkyl of from 1 to about 6 carbon atoms; lower acyl of from 1 to about 6 carbon atoms; monocyclic aryl of about 6 to 8 carbon atoms; and monocyclic aralkyl, that is, an alkyl group having an aryl substituent thereon, wherein the alkyl group has 1 to about 5 carbon atoms and the aryl group has about 6 to 8 carbon atoms. Also disclosed are methods for making the above compounds.

REFERENCES:
patent: 3828081 (1974-08-01), Ercoli et al.
patent: 3989828 (1976-11-01), Aries

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