Buffering system for anticalculus dentifrices

Drug – bio-affecting and body treating compositions – Dentifrices – Fluorine or fluorine compound containing

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424 49, 424 57, 424717, A61K 716, A61K 718, A61K 3310

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active

052157407

ABSTRACT:
A dentifrice for inhibiting calculus formation, comprising sodium bicarbonate, one or more alkali metal pyrophosphate salts, a soluble fluoride ion source and other adjuvants, in admixture with a buffering agent selected from among an alkali metal orthophosphate, o-phosphoric acid, an alkali metal glycerophosphate, tri(hydroxymethyl)aminomethane, tartaric acid or citric acid. The buffering agent is incorporated in the dentifrice in an amount of from about 0.1 to 2.5% by weight, sufficient to buffer the pH of the dentifrice to a value within the range of from about pH 8.2 to 8.9. The thus buffered dentifrice is subject to decreased risk of irritation of the oral mucosa or desquamation, as compared with dentifrices excluding such a buffering agent.

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