Method for the production of medical-grade lipid-coated microbub

Compositions – Inorganic luminescent compositions – Tungsten containing

Patent

Rate now

  [ 0.00 ] – not rated yet Voters 0   Comments 0

Details

424 2, 424 9, 436173, 12866202, 1286534, 514938, 252314, B01J 1300, A61K 4900, A61K 9107, B01F 304

Patent

active

052156800

ABSTRACT:
This invention relates to a large scale method for the production of medical grade lipid-coated microbubbles, to the paramagnetic labeling of such microbubbles and to therapeutic applications for the microbubbles. More particularly, the invention relates to a method of the production of medical grade, concentrated suspensions of stable, paramagnetically derivatized or underivatized microbubbles useful for ultrasonic and magnetic resonance imaging and also relates to therapeutic interventions such as selective tumor destruction.

REFERENCES:
patent: 4276885 (1981-07-01), Tickner et al.
patent: 4466442 (1984-08-01), Hilmann et al.
patent: 4572203 (1986-02-01), Feinstein
patent: 4684479 (1987-08-01), D'Arrigo
patent: 4774958 (1988-10-01), Feinstein
patent: 4832941 (1989-05-01), Berwing et al.
patent: 4900540 (1990-02-01), Ryan et al.
patent: 4927637 (1990-05-01), Morano et al.
patent: 4985233 (1991-01-01), Klaveness et al.
patent: 5078986 (1992-01-01), Bosworth et al.
patent: 5088499 (1992-02-01), Unger
Carr et al, "Intravenous Chelated Gadolinium As A Contrast Agent In NMR Imaging Of Cerebral Tumors", Lancet, pp. 484-486 (Mar. 3, 1984).
Lauffer et al, "Preparation and Water Relaxation Properties of Proteins Labeled with Paramagnetic Metal Chelates", Mag. Res. Imaging, 3:11-16 (1985).
Lauffer et al, "1/T.sub.1 NMRD Profiles of Solutions of Mn.sup.2+ and Gd.sup.3+ Protein-Chelate Conjugates", Mag. Res. Med., 3:541-548 (1986).
Quan et al, "Applicators for generating ultrasound-induced hyperthermia in neoplastic tumours and for use in ultrasound physiotherapy", Phys. Med. Biol., 34:1719-1731 (1989).
Runge et al, "Initial Clinical Evaluation of Gadolinium DTPA For Contrast-Enhanced Magnetic Resonance Imaging", Mag. Res. Imaging, 3:27-35 (1985).
ter Haar et al, "High intensity focused ultrasound--a surgical technique for the treatment of discrete liver tumours", Phys. Med. Biol., 34:1743-50 (1989).

LandOfFree

Say what you really think

Search LandOfFree.com for the USA inventors and patents. Rate them and share your experience with other people.

Rating

Method for the production of medical-grade lipid-coated microbub does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Method for the production of medical-grade lipid-coated microbub, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Method for the production of medical-grade lipid-coated microbub will most certainly appreciate the feedback.

Rate now

     

Profile ID: LFUS-PAI-O-1812441

  Search
All data on this website is collected from public sources. Our data reflects the most accurate information available at the time of publication.