Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Patent
1990-05-01
1992-06-09
Ivy, C. Warren
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
514333, 514334, 546256, 546257, 546258, 546262, 546265, C07D40112, C07D21322, A61K 31445
Patent
active
051207478
ABSTRACT:
Platelet activating factor antagonists of formula (I): ##STR1## wherein R is phenyl or phenyl substituted by one or more substituents selected from nitro, halo, C.sub.1 -C.sub.4 alkyl, C.sub.1 -C.sub.4 alkoxy, aryl(C.sub.1 -C.sub.4)alkoxy, fluoro(C.sub.1 -C.sub.4)alkoxy, C.sub.1 -C.sub.4 alkylthio, C.sub.1 -C.sub.4 alkylsulphonyl, hydroxy, trifluoromethyl and cyano, or is phenyl fused to a dioxole ring;
REFERENCES:
patent: 3971791 (1976-07-01), Meyer
patent: 4285955 (1981-08-01), Wehinger et al.
patent: 4414213 (1983-11-01), Poindexter et al.
patent: 4788205 (1988-11-01), Cooper et al.
patent: 4820842 (1989-04-01), Anderson et al.
Chemical Abstract, vol. 85, No. 78008h, Kazuo et al., 1975, "5-Carbamoyl-4-phenyl-26-dialkyl-1,4-dihydropyridine-3-carboxylic esters".
Cooper Kelvin
Fray Michael
Richardson Kenneth
Steele John
Covington Raymond
Ivy C. Warren
Lumb J. Trevor
McManus James M.
Pfizer Inc.
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