Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving nucleic acid
Patent
1998-06-09
1999-09-07
LeGuyader, John L.
Chemistry: molecular biology and microbiology
Measuring or testing process involving enzymes or...
Involving nucleic acid
4351723, 536 231, 536 235, 536 243, 536 2431, C07H 2104, C12Q 168
Patent
active
059486252
ABSTRACT:
The present invention provides a human ATP synthase d subunit (ASYSD) and polynucleotides which encode ASYSD. The invention also provides expression vectors, host cells, agonists, antisense molecules, antibodies, or antagonists. The invention also provides methods for producing ASYSD and for treating disorders associated with expression of ASYSD.
REFERENCES:
Database EMBL, European Bioinformatics Institute, Accession No. AA203548, Jan. 30, 1997, Hillier L. et al.: "zx59a08.rl Soares fetal liver spleen 1NFLS S1 Homo sapiens cDNA clone 446774" XP002071206 The WashU-Merck EST Project.
Database EMBL, European Bioinformatics Institute, Accession No. W19605, May 5, 1996, Hillier et al.: "zb32g11.rl Soares oarathyroid tumor NbHPA Homo sapiens cDNA clone 305348" XP002071207 The WashU-Merck EST Project.
Database Genbank, Acc. No. W01415, Apr. 18, 1996, Hillier, et al.: "za73c08.rl Soares fetal lung NbHL19W Homo sapiens cDNA clone 298190 5'" XP002071208 The WashU-Merck EST Project.
Database Genbank, Acc. No. W47097, Oct. 11, 1996, Hillier, et al.: "zc39f03.rl Soares senescent fibroblasts NbHSF Homo sapiens cDNA clone 324701 5'" XP002071209 The WashU-Merck EST Project.
Database Genbank, Acc. No. N44815, Feb. 13, 1996, Hillier, et al.: "yy24h02.rl Homo sapiens cDNA clone 272211 5'" XP002071210 The WashU-Merck EST Project.
Walker, J.E. et al., "Studies of the Gens for ATP Synthases in Eubacteria, Chloroplasts and Mitochondria: Implications for Structure and Function of the Enzyme", Chem. Scr., 27B: 97-105 (1987).
Database EST-STS on MPSRCH, accession No. AA081285, Feb. 4, 1996.
Goli Surya K.
Hillman Jennifer L.
Incyte Pharmaceuticals Inc.
LeGuyader John L.
Mohan-Peterson Sheela
Wang Andrew
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