Fused 1,2,5-oxadiazole-2-oxides and their use

Details Fused 1,2,5-oxadiazole-2-oxides and their use Fused 1,2,5-oxadiazole-2-oxides and their use

1993-05-25

1994-11-01

Fan, Jane T.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

548126, 546116, C07D49504, A61K 3141

Patent

active

053608127

ABSTRACT:
The present invention relates to fused 1,2,5-oxadiazole-2-oxides of the general formula I ##STR1## in which A denotes ##STR2## and X, Y, Z as well as R.sup.1, R.sup.2, R.sup.3 and n are defined as indicated in Claim 1, to processes for their preparation and to their use for the control and prevention of disorders of the cardiovascular system, in particular for the control and prevention of angina pectoris, and for the treatment of erectile dysfunctions.

REFERENCES:
patent: 4416893 (1983-11-01), Schonafinger
Paulmier et al., CA 84:43919h 1976.
Paulmier et al., CA 84:43941j 1976.
Von Dobeneck et al., CA 90:87350u 1979.
Noto et al., CA 111:56750x 1989.
J. Chem. Soc., Perkin Trans. 2, No. 2 (1989) pp. 127-130.
Chem. Abs., vol. 113, No. 3, (1990), Abs. No. 23596q.

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