Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Patent
1993-03-24
1994-11-01
Brust, Joseph Paul
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
514322, 514394, 546199, 546271, 5483044, 5483047, 5483061, C07D23508
Patent
active
053608097
ABSTRACT:
The present invention discloses compounds of the formula ##STR1## wherein X is C;
Y is C;
R.sup.4 to R.sup.7 and R.sup.11 to R.sup.13 are as defined herein; or a pharmaceutically-acceptable addition salt thereof. The compounds are useful as pharmaceuticals, for example, in the treatment of stroke, ischemia, anoxia, migraine and psychosis.
REFERENCES:
patent: 4492708 (1985-01-01), Spitzer
patent: 4503061 (1985-03-01), Bristol et al.
patent: 4550119 (1985-10-01), Morrison
patent: 4734415 (1988-03-01), Sircar et al.
patent: 5179210 (1993-01-01), Ebel
patent: 5210091 (1993-05-01), Axelsson et al.
Khristich et al., Chemistry of Heterocyclic Compounds vol. 18, No. 12, pp. 1299-1302 (Jun., 1983).
Axelsson Oskar
Christophersen Palle
Nielsen Elsebet O.
Peters Dan
Brust Joseph Paul
Gabilan Mary Susan H.
Hueschen Gordon W.
NeuroSearch A/S
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