6-(polyfluoroalkoxyphenyl) pyridazinones, their compositions, sy

Details 6-(polyfluoroalkoxyphenyl) pyridazinones, their compositions, sy 6-(polyfluoroalkoxyphenyl) pyridazinones, their compositions, sy

1985-05-07

1987-05-12

Berch, Mark L.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Heterocyclic carbon compounds containing a hetero ring...

544171, 544239, C07D23714, C07D23704, C07D29514, A61K 3150

Patent

active

046650741

ABSTRACT:
6-aryl-3[2H]pyridazinones of formula I ##STR1## in which one of the substituents R1 and R2 denotes hydrogen or (C1-C4)-alkoxy, and the other denotes polyfluoro-(C1-C4)-alkoxy, and their pharmacologically-tolerated salts are suitable as bronchospasmolytic and cardiotonic active compounds. Processes for their preparation and appropriate medicaments are indicated.

REFERENCES:
patent: 4397854 (1983-08-01), Sircar
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Steck et al., J. Heterocycl. Chem., vol. 11, 755-761, 1974.
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Schreiber et al., Bull. Soc. Chim., France, 2, 625-629, 1973.
Pitarch et al., Eur. J. Med. Chem.-Chimica Therapeutica, vol. 9, No. 6, 644-650, 1974.
Curran et al., J. Med. Chem., vol. 17, No. 3, 273-281, 1974.
Derwent #B03, 18917 1408 for JP8008-015, 1983.
Derwent #B03, 18918 1408 for JP58008016, 1983 Mitsubishi.
Derwent #B02, 16839 C/10 for EP 8391 (Thomae), 3/1980.
Derwent #B03 CO211413x/107 for DT 2435 244 (Lentia), 1974.
Derwent #B03, 33034 C/19 for EP 10156 (Merek), 1980.
Derwent #B03, 67389A/38 for DT2810267 (Sankyo), 9/78.
Derwent #B03, 49295B/27 for DT275923 (Hoechst), 1979.
Derwent B03 CO2 30268x/17 for DT2445681 (Lentia), 1976.

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