Renin-inhibiting aminodiol derivatives

Details Renin-inhibiting aminodiol derivatives Renin-inhibiting aminodiol derivatives

1993-01-06

1994-11-01

Lee, Lester L.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Peptide containing doai

530331, A61K 3702, C07K 508

Patent

active

053607910

ABSTRACT:
The invention relates to compounds of the formula I ##STR1## in which A denotes a radical of the formula II ##STR2## in which E denotes a CH.sub.2 group or an NR.sup.9 radical,

REFERENCES:
Plattner et al. J. Med. Chem. 1988, 31(12):2277-2288.
Burger. Medicinal Chemistry. 1960. pp. 565-571, 578-581, 600-601.
Hanson et al., Biochemical and Biophysical Research Communications, vol. 132, No. 1, pp. 155-161. (Oct. 15, 1985).
Hanson et al., Biochemical and Biophysical Research Communications, vol. 146, No. 3, pp. 959-963 (Aug. 14, 1987).
Kleinert et al., FEBS letters, vol. 230, No. 1, 2, pp. 38-42 (Mar. 1988).
Thaisrivongs et al., Journal of Med. Chem. V. 30, pp. 976-982 (1987).

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