Production of herpes simplex viral protein

Details Production of herpes simplex viral protein Production of herpes simplex viral protein

1982-07-20

1989-04-04

Martinell, James

Chemistry: molecular biology and microbiology

Micro-organism, tissue cell culture or enzyme using process...

Enzymatic production of a protein or polypeptide

435 70, 435 71, 4351721, 4351723, 4352401, 4352402, 435243, 43525233, 435255, 435256, 435320, 536 27, 935 12, 935 28, 935 29, 935 52, 935 66, 935 69, 935 70, 935 72, 935 73, C12P 2100, C12P 2102, C12P 2104, C12N 1500, C12N 500, C12N 100, C12N 120, C12N 116, C12N 118, C07H 2104

Patent

active

048186945

ABSTRACT:
Methods and composition are provided for the cloning and expression of a Herpes Simplex Virus (HSV) glycoprotein (gD) gene in single-cell host organisms. Also described are methods for culturing these novel single-cell organisms to produce the HSV-gene product. The HSV gD-related polypeptide produced by the recombinant DNA techniques described herein may be formulated for use as an immunogen in a vaccine to protect against HSV-1 and HSV-2 infection.

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