Particulate agents

Details Particulate agents Particulate agents

1995-06-07

1999-09-07

Dees, Jose G.

Drug, bio-affecting and body treating compositions

Radionuclide or intended radionuclide containing; adjuvant...

Coated, impregnated, or colloidal particulate

424 111, 424 137, A61K 5100, A61M 3614

Patent

active

059483849

ABSTRACT:
A novel means of pharmaceutical delivery for therapy of prophylaxis or to assist surgical or diagnostic operations on the living body is provided by neuronal endocytosis and axonal transport following pharmaceutical administration into vascularized, peripherally innervated tissue, e.g. intramuscular injections of a nerve adhesion molecule in coupled particle comprising a physiologically active substance or a diagnostic marker.

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Gallagher, J.E., G. George, A.R. Brody (1987) "Sialic acid mediates the initial binding of positively charged inorganic particles to alveolar macrophage membranes" Am. Rev. Respir. Dis. 135(6):1345-1352 (abstract only).
Menetrey, D. (1985) "Retrograde tracing of neural pathways with a protein-gold complex" Histochemistry 83(5):391-395 (abstract only).

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