Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving antigen-antibody binding – specific binding protein...
Patent
1995-06-05
1997-12-23
Housel, James C.
Chemistry: molecular biology and microbiology
Measuring or testing process involving enzymes or...
Involving antigen-antibody binding, specific binding protein...
435 79, 435 792, 435 793, 435 794, 436507, 436536, 4242771, 4241411, 4241421, G01N 3353, G01N 33564, A61K 3900
Patent
active
057006490
ABSTRACT:
The present invention describes Urinary Tumor Associated Antigen (UTAA), its isolation and use in diagnostic assays. In particular, UTAA has been identified in samples from cancer patients, in some cases as part of an immune complex of UTAA and UTAA-specific immunoglobulin. Isolated UTAA also may be formulated as a pharmaceutical for production of antibodies or as a vaccine.
REFERENCES:
patent: 4376110 (1983-03-01), Graver et al.
patent: 4707438 (1987-11-01), Oh
patent: 4946774 (1990-08-01), Kung et al.
patent: 5250297 (1993-10-01), Keydar
patent: 5292636 (1994-03-01), Carney et al.
patent: 5401638 (1995-03-01), David et al.
Huth et al. Cancer, vol. 49, 1982 pp. 1150-1157.
Euhus et al. 24th Annual Meeting of the American Society of Clinical Oncocolgy Proceedings May 22-24 1988.
Gupta et al. Diagnostic Immunology (1):303-309 1983.
Bystryn et al, "Preparation and Characterization of a Polyvalent Human Melanoma Antigen Vaccine," Journal of Biological Response Modifiers, 5:211-224, 1986.
Dunbar et al., "Protein Analysis Using High-Resolution Two-Dimensional Polyacrylamide Gel Electrophoresis," Methods in Enzymology, 182:441-443, 1990.
Euhus et al., "A Murine Monoclonal Antibody to a Glycoprotein Tumor Associated Antigen in Sera and Urine of Melanoma Patients," AACR, Abstract No. 1566, 1988.
Euhus et al., "Demonstration and Isolation of a Glycoprotein Tumor Associated Antigen from Sera of Melanoma Patients," Proceedings of American Society of Clinical Oncology, Abstract No. 169, 7:44, Mar., 1988.
Euhus et al., "Induction of antibodies to a tumor-associated antigen by immunization with a whole melanoma cell vaccine," Cancer Immunol. Immunother., 29:247-254, 1989.
Gupta et al., "Immunologic Similarity Between Tumor-Associated Antigens Detected in Urine of Melanoma Patients and Those Expressed by Melanoma Cells," Proceedings of American Society of Clinical Oncology, Abstract No. C-35, p. 9, Mar., 1984.
Gupta et al., "Increase in Antibody Level to a Tumor Associated Antigen in Melanoma Patients Undergoing Immunotherapy with a Tumor Cell Vaccine," Proceedings of American Society of Clinical Oncology, Abstract No. 979, 6:249, Mar., 1987.
Huth et al., "Purification of Antigens From Urine of a Sarcoma Patient by Affinity Chromatography," Journal of Surgical Oncology, 18:237-247, 1981.
Paulie et al., "Monoclonal antibodies to antigens associated with transitional cell carcinoma of the human urinary bladder," Cancer Immunol. Immunother., 17:173-179, 1984.
Rote et al., "Determination of Incidence and Partial Characterization of Tumor-Associated Antigens Found in the Urine of Patients Bearing Solid Tumors," Int. J. Cancer, 26:203-210, 1980.
Wong et al., "Demonstration of a Well-Characterized Tumor-Associated Antigen on Melanoma Cell Surface," Journal of Surgical Oncology, 38:147-150, 1988.
Euhus David M.
Gupta Rishab K.
Morton Donald L.
Housel James C.
Shaver Jennifer
LandOfFree
Method of detection of urinary tumor associated antigen does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Method of detection of urinary tumor associated antigen, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Method of detection of urinary tumor associated antigen will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-1801834