Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving nucleic acid
Patent
1995-03-01
1997-12-23
Saunders, David
Chemistry: molecular biology and microbiology
Measuring or testing process involving enzymes or...
Involving nucleic acid
435 75, 435 795, 436508, 436513, C12Q 168, G01N 33564
Patent
active
057006415
ABSTRACT:
Synthesized telomeric sequences bind to and can be used for detecting anti-DNA antibodies in serum. Autoimmune diseases such as Lupus Erythematosus, Rheumatoid Arthritis, and Scleroderma, can be detected by detecting an elevated level of anti-DNA antibodies using telomeric sequences. Test kits for such detection are provided including immobilized telomeric sequences capable of binding anti-DNA antibodies. Pharmaceutical compositions for inhibiting or reducing the activity of anti-DNA antibodies contain an effective amount of telomeric sequences effective in inhibiting the antibodies specific to the patient treated.
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