Chemistry of carbon compounds – Miscellaneous organic carbon compounds – C-metal
Patent
1981-04-13
1983-02-15
Rizzo, Nicholas S.
Chemistry of carbon compounds
Miscellaneous organic carbon compounds
C-metal
424270, 260239A, C07D49902, A61K 31425
Patent
active
043740650
ABSTRACT:
This invention relates to 2-substituted and 2,6-disubstituted penem compounds of the formula ##STR1## wherein Y is hydrogen, halo or certain organic radicals and X represents certain hereto-interrupted substituted alkyl radicals. Also included in the invention are pharmaceutically acceptable salts of the above compounds and derivatives of the above compounds in which the carboxyl group at the 3-position is protected as by an easily removable ester protecting group. The compounds of the present invention are potent antibacterial agents or are of use as intermediates in the preparation of such agents.
REFERENCES:
patent: 3950357 (1977-04-01), Kahan
patent: 4000154 (1976-12-01), Gleason et al.
patent: 4051132 (1977-09-01), Firestone
patent: 4070477 (1978-01-01), Ernest et al.
patent: 4155912 (1979-05-01), Menard et al.
patent: 4168314 (1979-09-01), Christensen
patent: 4182711 (1980-01-01), Veda
patent: 4182711 (1980-01-01), Ueda
Woodward et al., ACTA Pharma Suecica 14(Suppl), 23-25, (1977).
Fisher et al., Ann Reports, Med. Chemistry 13, 239-248, (1978).
Brown et al., JCS Chem. Comm., 359-360, (1977).
Eglington, JCS Chem. Comm., 1967, 720.
JCS Chem. Comm., 1979, pp. 663-664.
Martel Alain
Menard Marcel
Bristol-Myers Company
Morse David M.
Rizzo Nicholas S.
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