Nonaromatic fluoroallylamine MAO inhibitors

Organic compounds -- part of the class 532-570 series – Organic compounds – Amino nitrogen containing

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564500, 564501, 564504, 564508, 514671, C07C 8724

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active

046509070

ABSTRACT:
Novel nonaromatic fluoroallylamines are potent MAO inhibitors and at low dose selectively inhibit MAO-B. They are useful in the treatment of depression and coadministered with L-dopa, in the treatment of Parkinsonism.

REFERENCES:
patent: 4454158 (1984-06-01), Toraude
C. L. Johnson, J. Med. Chem., 19(5), 600 (1976).
C. Sahlberg et al., J. Med. Chem. 2(7), 1036 (1983).
R. R. Rando and A. Eigner, Molecular Pharmacology, 13, 1005 (1977).
Y. C. Martin, W. B. Martin and J. D. Taylor, J. Med. Chem. 18(9), 883 (1975).
R. L. White, R. A. Smith and A. Krantz, Biochemical Pharmacology 32,(23), 3661 (1983).
I. A. McDonald, J. Med. Chem., 28(2), 186 (1985).
T. Fujita, J. Med. Chem., 16(8), 923 (1973).
J. Knoll et al., Biochemical Pharmacology, 27(13), 1739 (1978).
M. Tenne et al., J. Neurochem., 44(5), 1373 (1985).

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