Hydrogenation of substituted, unsaturated hydantoins to substitu

Details Hydrogenation of substituted, unsaturated hydantoins to substitu Hydrogenation of substituted, unsaturated hydantoins to substitu

1985-12-03

1987-03-17

Schwartz, Richard A.

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

548311, 548312, 548313, 548314, C07D23374

Patent

active

046508767

ABSTRACT:
Unsaturated hydantoins are reduced to the corresponding saturated hydantoin by carrying out the hydrogenation reaction using a nickel catalyst in the presence of more than a stoichiometric amount of caustic. Use of this process allows for almost complete hydrogenation in short reaction times and also allows the reaction to be done using aqueous solvents and low levels of catalyst.
Frothing or foaming of the hydrogenation reaction mixture at elevated concentrations of hydantoin is overcome by incremental addition of hydantoin to the hydrogenation reaction mixture.

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