Analgesic and morphine antagonistic 2'-hydroxy-2-(5-isoxazolyl-m

Details Analgesic and morphine antagonistic 2'-hydroxy-2-(5-isoxazolyl-m Analgesic and morphine antagonistic 2'-hydroxy-2-(5-isoxazolyl-m

1978-04-12

1979-01-09

Jiles, Henry R.

Drug, bio-affecting and body treating compositions

Antigen, epitope, or other immunospecific immunoeffector

Parasitic organism or component thereof or substance...

546 97, C07D22126, A61K 31445

Patent

active

041338880

ABSTRACT:
Compounds of the formula ##STR1## wherein R.sub.1 is methyl, ethyl or propyl; and R.sub.2 is hydrogen, methyl or ethyl; and non-toxic, pharmacologically acceptable acid addition salts thereof; the compounds as well as their salts are useful as analgesics and morphine antagonists.

REFERENCES:
patent: 3499906 (1970-03-01), Robinson et al.
patent: 3823150 (1974-07-01), Merz et al.
patent: 3853889 (1974-12-01), Monkovic et al.

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