Polycyclic chromenes useful as antidepressants and anorexics

Details Polycyclic chromenes useful as antidepressants and anorexics Polycyclic chromenes useful as antidepressants and anorexics

1977-11-18

1979-01-09

Friedman, Stanley J.

Drug, bio-affecting and body treating compositions

Antigen, epitope, or other immunospecific immunoeffector

Bacterium or component thereof or substance produced by said...

42424853, 42424854, 42424855, 42424856, 42424857, 42424858, A61K 2700

Patent

active

041338839

ABSTRACT:
Compounds of the formula (I): ##STR1## and salts thereof wherein R.sub.1 is hydrogen, alkyl of 1 to 4 carbon atoms or benzyl; R.sub.2 is hydrogen or alkyl of 1 to 4 carbon atoms or is joined to R.sub.1 so that the NR.sub.1 R.sub.2 moiety is a 5 -, 6- or 7-membered saturated heterocyclic ring; R.sub.3 is hydrogen, alkyl of 1 to 4 carbon atoms or acyl of 1 to 4 carbon atoms; R.sub.4 is an aromatic group; R.sub.5 is hydrogen or alkyl of 1 to 4 carbon atoms R.sub.6 is hydrogen or alkyl of 1 to 4 carbon atoms; X is --CH.sub.2 -- or an oxygen atom and the dotted line represents a single or double bond, are useful for inducing anorexia and for their mood-modifying effects.

REFERENCES:
patent: 3471520 (1969-10-01), Irmscher et al.
patent: 3506654 (1970-04-01), Fried

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