Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Carbohydrate doai
Patent
1985-10-15
1987-03-17
Friedman, Stanley J.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Carbohydrate doai
514161, 514277, 514356, 514419, A61K 3140, A61K 3144, A61K 3162, A61K 3170, A61K 31435
Patent
active
046507892
ABSTRACT:
The production of the neurotransmitter serotonin is increased through administration of a therapeutic composition which includes L-tryptophan in combination with a salicylate, pyridoxine, niacin and a carbohydrate such as fructose. Both the absolute free fraction and the relative amount of the albumin-bound fraction of serum L-tryptophan are increased so that transport of L-tryptophan from the blood plasma across the blood-brain barrier into the brain is increased. Once within the brain, L-tryptophan is converted to serotonin.
REFERENCES:
patent: 3172809 (1965-03-01), Montandraud
patent: 3278379 (1966-10-01), Mansor
patent: 3282778 (1966-11-01), Lobel
patent: 3312593 (1967-04-01), Sheen et al.
patent: 3698912 (1972-10-01), Winitz
patent: 4210637 (1980-07-01), Wurtman et al.
patent: 4472387 (1984-09-01), Laruelle et al.
patent: 4482567 (1984-11-01), Tamir et al.
patent: 4530790 (1985-07-01), Monoghan et al.
patent: 4551471 (1985-11-01), De Luca et al.
The Control of Brain Tryptophan Concentration, G. Curzon, Acta Vitamin. Enzymol., (Milano), 1975, pp. 69-71.
Mechanisms of Elevation of Rat Brain Tryptophan Concentration by Various Doses of Salicylate, A. A.-B. Badawy, Br. J. Pharmac., 1982, pp. 211-213.
The Effect of Sodium Salicylate on the Binding of L-Tryptophan to Serum Proteins, McArthur et al, J. Pharm. Pharmac., 1969, pp. 744-750.
The Effect of Tryptophan on Postoperative Endodontic Pain, Shpeen et al, Oral Surgery, Oral Medicine and Oral Pathology, vol. 58, 1984, pp. 446-449.
Tryptophan in the Treatment of Depression, Young et al, Adv. Exptl. Med. Biol., vol. 133, 1981, pp. 727-737.
How Foods Affect the Way You Feel, Good Housekeeping, "The Better Way", 1984, p. 222.
Commonwealth Medical Corporation of America
Friedman Stanley J.
Shurupoff Lawrence J.
LandOfFree
Method and composition for increasing production of serotonin does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Method and composition for increasing production of serotonin, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Method and composition for increasing production of serotonin will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-1788550