Porphyrin derivatives

Details Porphyrin derivatives Porphyrin derivatives

1984-03-14

1987-04-14

Berch, Mark L.

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

546 82, C07D48722, C07D51900, A61K 31555

Patent

active

046580239

ABSTRACT:
Porphyrin derivatives containing a dipyrido[1,2-a:3',2'-d]imidazole moiety and a porphyrin moiety therein and metal complexes thereof are disclosed. These derivatives possess enhanced oxygen-dependent DNA cleaving ability and are effective as anititumer agents.

REFERENCES:
Hashimoto et al, Chem. Abs. 99, 122139s, (1983).
Matsudo et al, in "Antitumor Antibiotics", (Carter, Ed.), vol. 63, pp. 191-210, (1978).
Lown, J. C. S. Chem. Comm., 1982, p. 1298.

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