Human dopamine receptor and its uses

Details Human dopamine receptor and its uses Human dopamine receptor and its uses

1992-08-10

1996-10-29

Parr, Margaret

Chemistry: molecular biology and microbiology

Spore forming or isolating process

435 691, 435 711, 4351721, 4351723, 4353201, 536 235, 930 50, 935 22, 935 23, 935 52, 935 55, C12N 500, C12N 1500, C12P 2106, C07H 1700

Patent

active

055696015

ABSTRACT:
The present invention is directed toward the isolation, characterization and pharmacological use of the human D4 dopamine receptor. The nucleotide sequence of the gene corresponding to this receptor and alleleic variant thereof are provided by the invention. The invention also includes recombinant eukaryotic expression constructs capable of expressing the human D4 dopamine receptor in cultures of transformed eukaryotic cells. The invention provides cultures of transformed eukaryotic cells which synthesize the human D4 dopamine receptor, and methods for characterizing novel psychotropic compounds using such cultures.

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