Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving nucleic acid
Patent
1994-03-14
1996-10-29
Zitomer, Stephanie W.
Chemistry: molecular biology and microbiology
Measuring or testing process involving enzymes or...
Involving nucleic acid
935 77, 935 78, C12Q 168
Patent
active
055695841
ABSTRACT:
The present application is directed to a method for distinguishing between normally differentiated and benign or malignantly transformed cells in human colonic tissue. It is also directed to a method for monitoring the state of premalignant or malignant human colonic tissue. In both methods, a 50F1 complementary DNA standard probe is utilized which hybridizes to the RNA in the test sample and to a second sample, which is a predetermined sample of colonic tissue, and the amount of hybridization of the 50F1 complementary DNA to the test sample is compared to the hybridization of the 50F1 complementary DNA with the second sample.
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Montefiore Medical Center
Zitomer Stephanie W.
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