Combinations of anthelmintically active agents

Details Combinations of anthelmintically active agents Combinations of anthelmintically active agents

1995-06-01

1996-07-16

Jordan, Kimberly

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Heterocyclic carbon compounds containing a hetero ring...

514214, 5142222, 5142225, 5142238, 5142268, 5142282, 5142288, 5142292, 5142332, 514241, 514242, 514244, 514250, 514450, A61K 3155, A61K 3154, A61K 31535, A61K 3153

Patent

active

055367151

ABSTRACT:
Pharmaceutical compositions comprising a compound of formula (I) and at least one other anthelmintically active compound, being an avermectin or a milbemycin, are useful in the treatment of helminthiasis. In formula (I): R is optionally substituted phenyl, C.sub.3-8 cycloalkyl, C.sub.5-8 cycloalkenyl, C.sub.1-8 straight or branched chain alkyl, C.sub.2-8 straight or branched alkenyl, a 5- or 6-membered heterocyclyl, or optionally substituted phenyl C.sub.1-4 alkyl; each of Y and Z, which may be the same or different, is oxygen or sulfur; and X is a bond, a methylene group (--CH.sub.2 --), or oxygen.

REFERENCES:
patent: 4468390 (1984-08-01), Kitano
patent: 4661489 (1987-04-01), Dorgan et al.
Dialog record 1983677, Martindale ID: 2490-al-y, Dec. 1989.

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