Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Patent
1996-05-06
1998-02-17
Shah, Mukund J.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
548416, 540472, A61K 3140, C07D48714
Patent
active
057191751
ABSTRACT:
This invention provides novel bis-indolemaleimide macrocycle derivatives of the formula: ##STR1## The invention further provides the preparation, pharmaceutical formulations and the methods of use for inhibiting Protein Kinase C in mammals.
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Heath, Jr. William F.
Jirousek Michael R.
McDonald, III John H.
Rito Christopher J.
Boone David E.
Caltrider Steven P.
Eli Lilly and Company
Shah Mukund J.
Sripada Pavanaram K.
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