Organic compounds -- part of the class 532-570 series – Organic compounds – Carbohydrates or derivatives
Patent
1993-09-29
1994-11-08
Brown, Johnnie R.
Organic compounds -- part of the class 532-570 series
Organic compounds
Carbohydrates or derivatives
514 30, C07H 1704, A61K 3170
Patent
active
053628624
ABSTRACT:
An improved process for formation of a 5-oxime on avermectin derivatives comprises the treatment of the oxo compound with O-(trimethylsilyl)hydroxylamine in the presence of a Lewis acid.
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patent: 4427663 (1984-01-01), Mrozik
patent: 4547520 (1985-10-01), Ide et al.
patent: 5015630 (1991-05-01), Fisher et al.
patent: 5023241 (1991-06-01), Linn et al.
Tetrahedron Letter, No. 45, pp. 4313-4316 (1971), by T. M. Chau, et al.
Agri & Biol. Chem. vol. 55 (10), pp. 2615-2621 (1991) by Y. Tsukamoto, et al.
Amato Joseph S.
Cvetovich Raymond
Brown Johnnie R.
DiPrima Joseph F.
Lee Howard C.
Merck & Co. , Inc.
Rose David L.
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