Controlled, sustained release delivery system for smoking cessat

Drug – bio-affecting and body treating compositions – Preparations characterized by special physical form – Web – sheet or filament bases; compositions of bandages; or...

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424423, 424425, 424426, 424451, 424489, 424501, 424502, 514810, 514811, 514812, 514813, 514953, 514955, 514963, 514965, A61K 970, A61K 948, A61K 950, A61F 202

Patent

active

055365035

ABSTRACT:
A drug delivery system useful in aiding individuals in the cessation of smoking or chewing nicotine containing products is described. The delivery system includes a physical constraint modulation system (PCMS.TM.) containing lobeline. The drug delivery system is capable of delivering lobeline to an individual in a controlled, sustained release manner and providing long-term therapeutic levels of lobeline to the individual. The delivery of lobeline in such a manner reduces or eliminates the individual's smoking or chewing habit. The PCMS may be a biodegradable polymer containing the lobeline capable of subcutaneous or intramuscular injection or implantation into the individual or may be part of a transdermal patch containing lobeline. Also described are methods of using the drug delivery systems and kits containing the drug delivery systems.

REFERENCES:
patent: 3887699 (1975-06-01), Yolles

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