Methods of using diethyldithiocarbamic acid for the prevention o

Details Methods of using diethyldithiocarbamic acid for the prevention o Methods of using diethyldithiocarbamic acid for the prevention o

1993-09-15

1994-11-08

Seigel, Alan

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

N-c doai

A61K 3127

Patent

active

053627482

ABSTRACT:
The subject invention relates to methods for regulating hair growth in mammalian skin comprising topical application of diethyldithiocarbamic acid ("DEDCA") or a pharmaceutically-acceptable salt thereof. The subject invention further involves topical compositions comprising DEDCA.

REFERENCES:
patent: 4814351 (1989-03-01), Mathews et al.
Blumenkrantz N. and L. Blomstedt, "Chelators Depigmant and Increase Elasticity of Mink Skin", Acta. Agric. Scand., vol. 37, pp. 375-395, (1987).
Milas, L., N. Hunter, H. Ito, and L. J. Peters, "In Vivo Radioprotective Activities of Diethyldithiocarbamate (DDC)", Int. J. Radiation Oncology Biol. Phys., vol. 10, pp. 2335-2343, (1984).
Schoental, R., "Irreversible Depigmentation of Hair by N-Methyl-N-Nitrosourethane", Experientia, vol. 27, pp. 552-553, (1987).
Sunderman, F. W., "Use of Sodium Diethyldithiocarbamate in the Treatment of Nickel Carbonyl Poisoning", Annals of Clinical and Laboratory Science, vol. 20, No. 1, pp. 14-21, (1990).

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