Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Patent
1992-02-25
1994-11-08
Ivy, C. Warren
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
514307, 546 90, 546141, 546143, 546147, C07D49100, A01N 4342
Patent
active
053627369
ABSTRACT:
Novel isoquinoline derivatives represented by formula (I): ##STR1## wherein R.sup.1, R.sup.2, R.sup.3, R.sup.4, R.sup.5, X.sup.1 and X.sup.2 are as defined in the specification, have an anti-arrhythmic activity and bradycardiac activity and are effective for the treatment of arrhythmia, myocardiac infarction or angina pectoris.
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patent: 4613606 (1986-09-01), Clark et al.
patent: 4851537 (1989-07-01), Noyori et al.
patent: 4963563 (1990-10-01), Franzmann et al.
patent: 4963684 (1990-10-01), Morita et al.
Chemical Abstracts, vol. 61, No. 2 Jul. 20, 1964, Col. 1829c-1830d, Columbus, Ohio, US; I. Kazuyoshi et al.: "Influence . . . Synthesis".
Hayama Takashi
Ishikawa Kiyofumi
Nishikibe Masaru
Yano Mitsuo
Banyu Pharmaceutical Co. Ltd.
Covington Raymond
Ivy C. Warren
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