Resin method for making sulfoxide for solid phase peptide synthe

Details Resin method for making sulfoxide for solid phase peptide synthe Resin method for making sulfoxide for solid phase peptide synthe

1986-12-30

1989-01-31

Henderson, Christopher

Synthetic resins or natural rubbers -- part of the class 520 ser

Synthetic resins

Mixing of two or more solid polymers; mixing of solid...

5253594, 525387, C08F 834, C08F 806

Patent

active

048016659

ABSTRACT:
A resin for solid phase peptide synthesis and a method for synthesizing the resin wherein the resin has a sulfoxide linkage which is stable to strong acid deprotecting conditions. The linkage can be reduced to a sulfide linkage which allows cleavage of the peptide from the resin under mild acid conditions.

REFERENCES:
patent: 3995094 (1976-11-01), Crosby

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