Mercapto-acylamino acid antihypertensives

Details Mercapto-acylamino acid antihypertensives Mercapto-acylamino acid antihypertensives

1987-03-27

1989-01-31

Rotman, Alan L.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Ester doai

558254, 558417, 564153, 564154, 560 10, 560 16, 560 17, 560 18, 562426, 562427, 562432, 514522, 514513, 514529, 514532, 514540, 514562, C07C10300, C07C14940, C07C14943, C07C147107

Patent

active

048016098

ABSTRACT:
Novel mercapto-acylamino acids useful in the treatment of hypertension and combinations of mercapto-acylamino acids and atrial natriuretic peptides useful for treating hypertension are disclosed.

REFERENCES:
patent: 4053651 (1977-10-01), Ondetti et al.
patent: 4329495 (1982-05-01), Bindra
patent: 4401677 (1983-04-01), Greenberg et al.
patent: 4513009 (1985-04-01), Roques et al.
patent: 4740499 (1988-04-01), Olins
Griffith, Ann. Rev. Biochem., 1986, pp. 855-878.
Needleman et al, N. Eng. J. Med., 314, 13 (1986) pp. 828-834.
Cantin et al, Scientific American, 254 (1986) pp. 76-81.

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