Stable topical anesthetic compositions

Details Stable topical anesthetic compositions Stable topical anesthetic compositions

1976-04-02

1977-10-04

Ore, Dale R.

Drug, bio-affecting and body treating compositions

Antigen, epitope, or other immunospecific immunoeffector

Recombinant or stably-transformed bacterium encoding one or...

424313, A61K 31245

Patent

active

040525139

ABSTRACT:
A cosmetically elegant and stable oil in water emulsion for use as a topical anesthetic containing 0.5-15% benzocaine solubilized in water with a dialkyl ester of an alkanedioic acid having the formula ROOC--C.sub.n H.sub.2n --C00R' where R and R' are alkyl groups of from 1 to 4 carbon atoms and n is an integer from 1 to 8.

REFERENCES:
patent: 1888601 (1932-11-01), Mack et al.
patent: 1907392 (1933-05-01), Stover
patent: 2340776 (1944-02-01), Stambovsky
patent: 2382546 (1945-08-01), Curtis
patent: 2457188 (1948-12-01), Stone
patent: 3322624 (1967-05-01), Stone
patent: 3479428 (1969-11-01), Bryce et al.
patent: 3751562 (1973-08-01), Nichols
patent: 3821363 (1974-06-01), Black et al.
De Navarre, International Encyclopedia of Cosmetic Material Trade Names, 1957, pp. 323 and 11.

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