Use of ciclopirox or a pharmaceutically acceptable salt thereof

Details Use of ciclopirox or a pharmaceutically acceptable salt thereof Use of ciclopirox or a pharmaceutically acceptable salt thereof

1996-01-19

1998-12-08

Criares, Theodore J.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

A61K 3144

Patent

active

058469842

ABSTRACT:
6-Cyclohexyl-1-hydroxy-4-methyl-2(1H)-pyridinone, also known as ciclopirox, and its salts such as ciclopirox olamine are used to inhibit neuronal cell damage or neuronal cell death.

REFERENCES:
patent: 3644626 (1972-02-01), Witzel
patent: 3655897 (1972-04-01), Witzel
patent: 3883545 (1975-05-01), Lohaus et al.
patent: 4185106 (1980-01-01), Dittmar et al.
patent: 4711775 (1987-12-01), Dittmar et al.
patent: 5231112 (1993-07-01), Janoff et al.
Abstracts, 19: 885 (1993).
Ferrari, G. and Greene, L.A. (1994). Proliferative inhibition by dominant-negative Ras rescues naive and neuronally differentiated PC12 cells from apoptotic death. The EMBO Journal, 13: 5922-5928 and;.
Brooks, S.F. et al., (1993). Apoptosis induced by NGF-withdrawal from differentiated PC12 cells involved activation of p34.sup.cdc2 kinase. Society For Neuroscience Abstracs, 19: 885.
Farinelli, S.E. et al., (1993). A possible link between the cell cycle and apoptosis of PC12 cells. Society For Neuroscience.
Urbani, L. et al., (1995). Dissociation of nuclear and cytoplasmic cell cycle progression by drugs employed in cell synchronization. Experimental Cell Research, 219: 159-168.

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