Method of preparation of 3-methylenecephams

Details Method of preparation of 3-methylenecephams Method of preparation of 3-methylenecephams

1976-04-02

1977-10-04

Rizzo, Nicholas S.

Organic compounds -- part of the class 532-570 series

Organic compounds

Chalcogen in the nitrogen containing substituent

424246, 260239A, 544 16, C07D50102

Patent

active

040523870

ABSTRACT:
Penicillin sulfoxide derived azetidinone sulfinyl chlorides and related sulfinic acid derivatives are cyclized to 3-methylenecephams by reaction with Friedel-Crafts catalysts or metathetic cation forming agents.

REFERENCES:
patent: 3960851 (1976-06-01), Kukolja et al.

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