Substituted cyclohexane derivatives, processes for their prepara

Details Substituted cyclohexane derivatives, processes for their prepara Substituted cyclohexane derivatives, processes for their prepara

1993-09-07

1995-10-31

Springer, David B.

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

518253, 518494, 5183047, 51830871, 560115, 560 24, C07D 2504, C07D40108, C07D40308, A61K 3147, A61K 31415, A61K 3141

Patent

active

054630622

ABSTRACT:
Cyclohexane derivatives of the formula I ##STR1## in which the radicals R.sup.1 to R.sup.6, X, Y and Z have the stated meanings, and processes for the preparation of these compounds are described. The compounds have valuable pharmacological properties and can therefore be used as pharmaceuticals.

REFERENCES:
E. Haslam et al., "the Shikimate Pathway. Part II. Conformational Analysis of (-)-Quinic Acid and Its Derivatives by Proton Magnetic Resonance Spectroscopy," J. Chem. Soc., pp. 1496-1500 (1971).
J. Soodsma et al., "The Inhibition by Phlorizin of Kidney Microsomal Inorganic Pyrophosphate-Glucose Phosphotransferase and Glucose 6-Phosphatase," J. Biol. Chem. 242, pp. 1955-1960 (1967).
B. Wallin et al., "The Requirement for Membrane Integrity in the Inhibition of Hepatic Glucose 6-Phosphatase by Sulfhydryl Reagents and Taurocholate," Biochem. Biophys. Res. Commun. 48, pp. 694-699 (1972).
M. Zoccoli et al., "Effect of Two Inhibitors of Anion Transport on the Hydrolysis of Glucose 6-Phosphate by Rat Liver Microsomes," J. Biol. Chem. 255, pp. 1113-1119 (1980).

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