Substituted N-(3-phenylthiopropyl)-3,3-diphenyl-propylamines pos

Organic compounds -- part of the class 532-570 series – Organic compounds – Amino nitrogen containing

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Details

26032614T, 2603437, 26050118, 26050119, 424262, 424280, 424316, 424330, A01N 3302, A01N 4308, C07C 8728, C07C14300

Patent

active

042462010

ABSTRACT:
Compound of formula: ##STR1## wherein R represents hydrogen or an alkyl group having from 1 to 4 carbon atoms; R', R", R'" and R"", equal or different from each other represent hydrogen atoms or OH groups, with the limitation that when R', R", R'" and R"" are all hydrogen atoms R cannot be an hydrogen atom and their salts with organic and inorganic pharmaceutically acceptable salts.
The process for the preparation of the compounds of the above general formula are disclosed.
The compounds show a good pharmacological activity and can be used as antiulcer, antispastic spasmolytic drugs.
The compounds can be administered as different pharmaceutical preparations containing an effective dose of the compound in combination or in admixture with excipients suitable for oral or parenteral administration or for topical use.

REFERENCES:
patent: 3884939 (1975-05-01), Bianchini et al.
Burger, "Medicinal Chemistry", Third Ed., Part II, pp. 1562-1569, (1970).

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