Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Patent
1995-06-07
1997-01-07
Chang, Ceila
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
514340, C07D41704, A61K 3144
Patent
active
055917550
ABSTRACT:
The present invention relates to therapeutically active azacyclic compounds, a method of preparing the same and to pharmaceutical compositions comprising the compounds. The novel compounds are useful as stimulants of the cognitive function of the forebrain and hippocampus of mammals and especially in the treatment of Alzheimer's disease, severe painful conditions and glaucoma.
REFERENCES:
patent: 4837241 (1989-06-01), Jensen
patent: 4933353 (1990-06-01), Jenssen
patent: 5017618 (1992-12-01), Border
Tune et al. "Anticolinergic delirium caused by topical homatropine ophthalmologic solution" Index Medicus 330504 (1992).
Sugrue "The pharmacology of antiglaucoma drugs" Pharm. Ther. v. 43, pp. 91-138 (1989).
Bodor et al. "Improved delivery through biological membrane" J. Med. Chem. v. 31, p. 100-106 (1988).
Wilbraham et al. "Organic and biological chemistry" The Benjamin/Cummins Pub. pp. 266-269 (1985).
Sugrue "The Pharmacology of autiglaucoma" Pharma. Ther. 43 91-138 (1989) (reference pages not attached.).
Olesen Preben H.
Sauerberg Per
Chang Ceila
Lambiris, Esq. Elias J.
Novo Nordisk A S
Zelson Esq. Steve T.
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