Methods for detecting activated RAS oncogenes

Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving nucleic acid

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435 912, 435810, 436501, 436 63, 436811, 536 231, 536 241, 536 243, 536 2431, 536 2432, 536 2433, 935 19, 935 77, 935 78, 935 86, C12Q 168, C07H 2104

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055915825

ABSTRACT:
Molecules complementary to nucleotide sequences encoding mutant ras proteins which contain a single-base mutation in the codon encoding amino acids at position 13, 12 or 61 have been produced. These molecules are useful in methods of detecting specific single-base mutations in altered ras genes and the specific cancers associated with such mutations.

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