Antibiotic A10255 complex and factors, and process and productio

Details Antibiotic A10255 complex and factors, and process and productio Antibiotic A10255 complex and factors, and process and productio

1991-07-17

1993-07-20

Chan, Y. Christina

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Peptide containing doai

514 11, 530317, 530323, 424117, 424118, 426635, 435 713, 435170, 435822, A61K 3702, A61K 3574, C07K 754, C12P 2100

Patent

active

052293629

ABSTRACT:
Newly-discovered antibiotic A10255 factors B, C, E, F, G, H, and J are produced by submerged aerobic fermentation of Streptomyces gardneri NRRL 15537 and NRRL 18260 or an A10255-producing variant or mutant thereof. The antibiotics are active against a wide variety of pathogenic bacteria, and also enhance feed-utilization efficiency in chickens, weanling pigs, cattle and sheep. The antibiotics can also be used to detect the thiostrepton-resistance gene in Streptomyces species.

REFERENCES:
patent: 3689639 (1972-09-01), Bergy et al.
patent: 4333923 (1982-06-01), Beck et al.
J. M. Liesch and K. L. Rinehart, "Berninamycin 3. Total Structure of Berninamycin A", J. Am. Chem. Soc., 99:5, Mar. 2, 1977.

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